Perivascular adipose tissue and inflammation

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Perivascular adipose tissue, vascular reactivity and hypertension.

Most blood vessels are surrounded by a variable amount of adventitial adipose tissue, perivascular adipose tissue (PVAT), which was originally thought to provide mechanical support for the vessel. It is now known that PVAT secretes a number of bioactive substances including vascular endothelial growth factor, tumor necrosis factor-alpha (TNF-α), leptin, adiponectin, insulin-like growth factor, ...

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Perivascular adipose tissue contains functional catecholamines

The sympathetic nervous system and its neurotransmitter effectors are undeniably important to blood pressure control. We made the novel discovery that perivascular adipose tissue (PVAT) contains significant concentrations of catecholamines. We hypothesized that PVAT contains sufficient releasable catecholamines to affect vascular function. HPLC, isometric contractility, immunohistochemistry, wh...

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Coronary Adventitial and Perivascular Adipose Tissue Inflammation in Patients With Vasospastic Angina.

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ژورنال

عنوان ژورنال: Obesity

سال: 2016

ISSN: 1930-7381

DOI: 10.1002/oby.21426